How Abuse-Deterrent Opioids Give Doctors and Patients More Options

first_img October 11, 2016 How Abuse-Deterrent Opioids Give Doctors and Patients More Options By: Sarah Galbally, Secretary of Policy and Planning SHARE Email Facebook Twitter Public Health,  Substance Use Disorder,  The Blog While many people become addicted to opioids by simply swallowing pills, others crush pills to snort or smoke.Drug manufacturers, with encouragement and guidance from the U.S. Food and Drug Administration, are rapidly developing new technologies to prevent this kind of abuse. Some of these drugs are uncrushable, even with a hammer, while others are formulated with naloxone so the more an individual takes, the less effective it is in creating a high and limiting the potential for overdose. Others turn into a gel when they are crushed, making them impossible to put into a syringe to inject.Recently, Governor Wolf sent a letter to the FDA encouraging their expedited approval of generic forms of opioids with abuse-deterrent formulations which will ultimately make these drugs more affordable and more accessible for the people who need them.Governor Wolf believes that insurance companies should be required to cover abuse-deterrent opioids. HB1698, which has passed in the House and is sponsored by Rep. Heffley, would require health insurance plans and carriers to provide access to abuse-deterrent opioids. In no way would this bill require doctors to prescribe abuse-deterrent opioids. Rather, it would give doctors additional decision making tools and create more opportunities for doctors and patients to collaborate on the best clinical path forward in treating pain.In 2010, OxyContin (OC) was reformulated to be abuse-deterrent. Following this reformulation, rates of abuse, misuse, overdose, death, and drug diversion all decreased. By 2013, “abuse of OxyContin decreased 48% in national poison center surveillance systems, decreased 32% in a national drug treatment system, and decreased 27% among individuals prescribed OC in claims databases. Doctor-shopping for OC decreased 50%,” according to a study published in the summer of 2016. While this study was limited to analyzing the effects of reformulated OC on OC-specific abuse, it adds to a growing body of evidence that justifies expanding access to opioids with abuse-deterrent properties for doctors and patients.According to the American College of Preventive Medicine, almost 60% of prescription medications that are used for nonmedical purposes are obtained from family or friends. Imagine a mother of teen children who was prescribed opioids for pain management following a car accident. Why wouldn’t we want to give this mother the option of having opioids that cannot be snorted or injected in her home?The disease of addiction often begins with swallowing pills. However as the severity of abuse and an individual’s tolerance increases, people suffering from addiction can quickly move to injecting and snorting opioids in order to achieve a stronger high.Furthermore, many also believe that the risk of addiction increases substantially with snorting or injecting. By making abuse-deterrent opioids more widely available, we can help to curb the likelihood of accelerating the severity of a person’s addiction and instead connect them with treatment services earlier in their addiction.Abuse-deterrent opioids are not a cure-all for the opioid epidemic, but taking steps to ensure that pills cannot be altered into forms that make them more potent is a positive step forward and one we wholeheartedly endorse in Pennsylvania.HB1698 requires that insurance companies over which the state has regulatory oversight (typically large and small group plans) provide coverage for three opioids with abuse deterrent properties in the event they currently offer a non-abuse deterrent opioid on their formulary. Neither Pennsylvania’s Medicaid program, Medical Assistance, nor the Commonwealth’s employee benefits plan, PEBTF, are covered under the purview of this legislation and yet both currently cover multiple abuse-deterrent opioids on their formularies. Private insurance companies should do their part to fight the opioid epidemic and model this coverage to create a pathway for meaningful consumer choice.Abuse-deterrent opioids, if crafted properly, can be important tools to prevent against intentional or unintentional misuse, abuse, or overdoses. Like Governor Tom Wolf on Facebook:   SHARE  TWEETlast_img read more

Moth states case for Classics

first_img The Ballydoyle trainer said: “She did it well. We thought she was nice last year, but she got beat a few times. I was giving the wrong instructions and instead of making use of her she should have been held up. “She’s able to change gears. It was a slow run race and she came from behind, which I imagine wouldn’t have suited. She quickened up well. She could go for a trial or head straight to Newmarket for the Guineas. It depends on what happens.” Stan James gave Moth a 16-1 quote for the 1000 Guineas, for which she would need to be supplemented O’Brien also reported his colts on course for the 2000 Guineas at Newmarket. “The wheels are still on,” he said. “Mars is still going that way and I’m very happy with Cristoforo Colombo. We also have George Vancouver and Pedro The Great and they are all still standing so far.” There will be more to look forward to for the Ballydoyle team with Duke Of Marmalade’s half-brother Ruler Of The World (2-1), who picked off the positively-ridden Manalapan in the Irish Stallion Farms EBF Maiden on his racecourse debut. O’Brien said: “I’m delighted with that horse. He had a few little setbacks and that’s why he didn’t run at two. He’s lazy and he just does what he has to. We’ll step him up gradually. He’ll go for a conditions race next and we’ll go gently with him. He’s a lovely horse, a sleepy horse, and there could be anything in there.” Aidan O’Brien’s three-year-old Moth looked every inch a Classic-bound filly as she made her seasonal bow a winning one in the Cancer Clinic Reasearch Trust EBF Fillies Maiden at the Curragh. An exquisitely bred and well-built daughter of Galileo, Moth (11-8 favourite) had been the market leader in both her late-season starts last year, looking a little too inexperienced to get off the mark, but she holds entries in the Irish 1000 Guineas and Investec Oaks. She travelled in behind under a very confident Joseph O’Brien and when switched wide for her run, her acceleration was dramatic and impressive as she galloped clear to score by four and a half lengths from Wannabe Better. center_img Press Associationlast_img read more

The BoxTrolls will be coming to the Wellington Regent this weekend

first_imgRotten Tomatoes rating (movie critics collective approval ratings): 74%. Audience review: 70% approval.Movies ahead at Regent Theater:Coming soon:OuijaAlexander.Rocky Horror Picture Show – Oct. 31.Follow us on Twitter. When: Friday at 7 p.m. Saturday and Sunday 2 p.m. and 7 p.m. This week at the Regent Theater: “The BoxTrolls.” (Movie trailer is below). Close Forgot password? Please put in your email: Send me my password! Close message Login This blog post All blog posts Subscribe to this blog post’s comments through… RSS Feed Subscribe via email Subscribe Subscribe to this blog’s comments through… RSS Feed Subscribe via email Subscribe Follow the discussion Comments Logging you in… Close Login to IntenseDebate Or create an account Username or Email: Password: Forgot login? Cancel Login Close Username or Email: Password: Lost your password? Cancel Login Dashboard | Edit profile | Logout Logged in as Admin Options Disable comments for this page Save Settings You are about to flag this comment as being inappropriate. Please explain why you are flagging this comment in the text box below and submit your report. The blog admin will be notified. Thank you for your input. There are no comments posted yet. Be the first one! Post a new comment Enter text right here! Comment as a Guest, or login: Login to IntenseDebate Login to Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Submit Comment Subscribe to None Replies All new comments Comments by IntenseDebate Enter text right here! Reply as a Guest, or login: Login to IntenseDebate Login to Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Cancel Submit Comment Subscribe to None Replies All new commentscenter_img Rated: PG. Time: 1 hour and 40 minutes. Movie Synopsis: A family event movie from the creators of “Coraline” and “ParaNorman” that introduces audiences to a new breed of family – The Boxtrolls, a community of quirky, mischievous creatures who have lovingly raised an orphaned human boy named Eggs (voiced by Isaac Hempstead-Wright) in the amazing cavernous home they’ve built beneath the streets of Cheesebridge. When the town’s villain, Archibald Snatcher (Academy Award winner Ben Kingsley), comes up with a plot to get rid of the Boxtrolls, Eggs decides to venture above ground, “into the light,” where he meets and teams up with fabulously feisty Winnifred (Elle Fanning). Together, they devise a daring plan to save Eggs’ family. Directors: Anthony Staachi and Graham Annable. (C) Focuslast_img read more